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Croscarmellose Sodium

Croscarmellose Sodium

Cross-linked sodium carboxymethylcellulose

Croscarmellose Sodium is an internally cross-linked sodium carboxymethylcellulose (CAS 74811-65-7), designated E468 and used as a tablet and capsule super-disintegrant, typically at 2 to 5%. The cross-linked structure is insoluble but swells rapidly on contact with water, generating the wicking and swelling force that breaks a dosage form apart for release. As a cross-linked modified polymer it is specified by grade rather than a single molecular formula or weight. It is supplied as a white to off-white fibrous powder and manufactured into tablets and capsules.

Made as
  • Tablets
  • Capsules

Applications

Disintegrant for compressed tablets and powder-filled capsules.

Documentation & quality

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How it’s controlled

  • Identity verified on every incoming raw material
  • Screened for heavy metals and microbial contaminants
  • Full batch and lot traceability
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