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Folate (Vitamin B9)

Quatrefolic (L-5-MTHF Glucosamine Salt)

(6S)-5-methyl-5,6,7,8-tetrahydrofolic acid, glucosamine salt

Quatrefolic is the glucosamine salt of (6S)-5-methyltetrahydrofolic acid (CAS 1181972-37-1; C32H51N9O16; MW 817.80), a fourth-generation reduced folate carrying the same single (6S) methylfolate anion as Metafolin but paired with a glucosamine counter-ion instead of calcium. It is produced by chemical synthesis, and the glucosamine used is shellfish- and animal-free. The amine counter-ion gives it greater water solubility than the calcium methylfolate and folinate salts, and its much higher molecular weight (817.80) reflects the larger glucosamine ion relative to the other folate forms. Like Metafolin it is a reduced 5-methyltetrahydrofolate rather than the oxidized folic acid or the 5-formyl calcium folinate. We manufacture it in capsules, tablets, softgels, powders, gummies and liquids.

可制成
  • 胶囊
  • 片剂
  • 软胶囊
  • 粉剂
  • 软糖
  • 液体

Applications

Multivitamins, B-complex supplements, single-nutrient capsules, gummies and liquid supplements.

Documentation & quality

Every order is backed by the documents your quality team files, and the controls behind them.

How it’s controlled

  • Identity verified on every incoming raw material
  • Screened for heavy metals and microbial contaminants
  • Full batch and lot traceability
  • Produced under our certified GMP system
See our certifications

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